RESEARCH FOCUS

GOZUACIK LAB, CELLULAR STRESS AND DEATH RESPONSES: Basic autophagy research and its implications in human health and disease.

“From high quality basic science to diagnosis and treatment of diseases”.

Research topics include:
– Elucidation of basic autophagy mechanisms and implications in diseases,  
– Cancer biology and autophagy, 
– Degenerative disease mechanisms and autophagy (e.g. Parkinson’s disease, rare diseases),
– Novel disease marker discovery and nano detection method development,  
-Discovery of novel drug targets and innovative patentable new drugs.
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Our research approach: 

In our lab, we discover regulators of stress responses and especially autophagy, including novel RNAs (e.g. microRNAs), proteins and metabolites, and characterize in detail their mechanisms of action and their implication in cellular and organismal pathways. 

Using our novel basic findings, we investigate how abnormalities of these stress responses are related to disease pathology, to disease progress, drug responses and prognosis.

Based on our discoveries, we are also interested in finding new diagnosis techniques, drug targets and innovative patentable drugs. We routinely use molecular biology, genetics, biochemistry, cell biology and in vivo animal experimentation techniques (CAM assays, mice experiments) and patient-derived cell and tissue analyses.

Therefore, our lab is a basic science and a pre-clinical medical research laboratory.

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More about us:

For our selected publications click here. 

For a full publication list click here.

For our recent microRNA-based drug-diagnosis patent click here.

For our awards click here. 

For TV and newspaper news about us click here.

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GOZUACIK Lab home.

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