Researcher – Tolga Sütlü

Tolga Sütlü

tolgasutlu@sabanciuniv.edu

+90 (216) 483 90 00 – 9887

-Immunology,
-Cancer Immunology,
-Cancer Immunotherapy,
-Gene Therapy,
-Lentiviral Vectors,
-Natural Killer Cells,
-Biosimilar Drugs

1. Kahraman T, Gucluler G, Simsek I, Yagci FC, Yildirim M, Ozen C, Dinc A, Gursel M, Ikromzoda L, Sutlu T, Gay S and Gursel I. Circulating LL37 targets plasma extracellular vesicles to immune cells and intensifies Behçet’s Disease severity. J Extracell Vesicles. 2017 Feb 28;6(1):1284449.
2. Duru AD, Sutlu T, Wallblom A, Uttervall K, Lund J, Stellan B, Gahrton G, Nahi H, Alici E. Deletion of Chromosomal Region 8p21 Confers Resistance to Bortezomib and Is Associated with Upregulated Decoy TRAIL Receptor Expression in Patients with Multiple Myeloma. PLoS One. 2015 Sep 17;10(9):e0138248.
3. Bestas B, Moreno PM, Blomberg KE, Mohammad DK, Saleh AF, Sutlu T, Nordin JZ, Guterstam P, Gustafsson MO, Kharazi S, Piatosa B, Nordin JZ, Roberts TC, Behlke MA, Wood MJ, Gait MJ, Lundin KE, El Andaloussi S, Mansson R, Berglöf A, Wengel J and Smith CI. Splice-correcting oligonucleotides restore BTK function in X-linked agammagloblunemia model. J. Clin. Invest. 2014 Sep 2;124(9):4067-81.
4. Sutlu T, Gilljam M, Stellan B and Alici E. Inhibition of intracellular anti-viral defense mechanisms augments lentiviral transduction of human natural killer cells: implications for gene therapy. Human Gene Therapy. 2012 Oct;23(10):1090-100.
5. Sutlu T, Stellan B, Gilljam M, Quezada HC, Nahi H, Gahrton G, Alici E. Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor. Cytotherapy. 2010 Dec;12(8):1044-55.

1. Evren Alici, Adil Duru, Tolga Sutlu “Enhanced Gene Delivery to Natural Killer Cells, Hematopoietic Stem Cells and Macrophages” WO2017059177A3

-Researcher, Sabancı University SUNUM (2018-current)
-Assistant Professor, Sabanci University FENS (2016-2018)
-Postdoctoral Researcher, Sabancı University (2014-2016)
-Postdoctoral Researcher, Karolinska University Hospital Huddinge (2012-2013)
-Molecular Biologist, Acibadem Genetic Diagnosis and Cell Therapy Center (2004-2005)

– Turkish Society of Immunology (Member of the Board)
– Molecular Biology Association of Turkey (Member of the Board, Treasurer)
– European Society of Gene and Cell Therapy (Member)