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2020 to date Full Professor, Koç University School of Medicine, Medical Biology Dept., Turkey.
2020 to date Senior Researcher, KUTTAM Research Center for Translational Medicine, Turkey.
2018 to date Part-Time Senior Researcher, SUNUM Nanotechnology Center, Turkey
2016 - 2020 Founding Board Member, EFSUN Nanodiagnostics Center of Excellence (efsun.sabanciuniv.edu), Turkey.
2006 – 2020 Professor, Sabanci University, Molecular Biology Genetics and Bioengineering Program, Turkey.
2001 – 2006 Postdoctoral Fellow, Weizmann Institute of Science, Israel (Prof. Kimchi)
Autophagy
Cell Death Mechanisms
Cancer
Tumor-Stroma
miRNAs
Cancer dormancy
Nanotechnology
Kocaturk NM, Peker N, … Gozuacik D. Novel protein complexes containing autophagy and UPS components regulate proteasome-dependent PARK2 recruitment onto mitochondria and PARK2-PARK6 activity during mitophagy. Cell Death Dis; 2022; 10;13(11):947. doi:10.1038/s41419-022-05339-x. (IF 9.68)
Akkoc Y, Dalci K, Karakas HE, ….. Gozuacik D. Tumor-derived CTF1 (cardiotrophin 1) is a critical mediator of stroma-assisted and autophagy-dependent breast cancer cell migration, invasion and metastasis. Autophagy; 2023;19(1):306-323. doi:10.1080/15548627.2022.2090693. (IF 13.39)
Demirbag-Sarikaya S, Akkoc Y, Turgut S, Erbil-Bilir S, Kocaturk NM, Dengjel J, Gozuacik Dx. A novel ATG5 interaction with Ku70 potentiates DNA repair upon genotoxic stress. Scientific Reports 2022. May 17;12(1):8134. doi: 10.1038/s41598-022-11704-9.
Uzuner D, Akkoç Y, Peker N, Pir P, Gozuacik D, Çakır T. Transcriptional landscape of cellular networks reveal interactions driving the dormancy mechanisms in cancer. Scientific Reports 2021. Aug 4;11(1):15806.
Akkoc Y, Peker N, Akcay A, Gozuacik Dx. Autophagy and Cancer Dormancy. Frontiers in Oncology, 2021, Mar 19;11:627023. DOI: 10.3389/fonc.2021.627023. (SCI Impact factor: 6.24).
1) Gozuacik D, Kutlu O, Akkoc Y, Akkiz H. IL as a novel biomarker and drug target in fatal liver cancer. WIPO-Patent Cooperation Treaty. Application Number: PCT/TR2019/051107. December 18, 2019. Pending.
2) Gozuacik D, Kutlu O, Kocaturk NM, Kilislioglu A, Karakus S, Kutlu M, Ilgar M, Ben Taleb AM, Tan E. Nano formulations comprizing Ceranib-2. WIPO-Patent Cooperation Treaty. Application Number: PCT/TR2019/050247. April 16, 2019. Pending.
3) Akgonul S, Zuvin M, Sevgen MI, Kosar A, Gozuacik D; Kutlu O, Yagci-Acar H. Rotary Magnetic Actuation System. WIPO-Patent Cooperation Treaty. Application Number: PCT/TR2019/050115. February 20, 2019. Pending.
4) Gozuacik D, Ozturk DG, Kocak M. Stress-Regulated MiRNAs As Novel Cancer Biomarkers. WIPO-Patent Cooperation Treaty. Application Number: PCT/TR2019/050004. January 2, 2018. Pending.
5) Yagci-Acar H, Gozuacik D, Kosar A, Unal O, Kocak M, Akkoc Y, Zuvin M. Therapeutic nanoparticles containing a protein for microRNA delivery and compositions and methods using same. WIPO-Patent Cooperation Treaty. Application Number: PCT/TR2018/050094. March 10, 2018. Pending.
6) Kosar A, Gozuacik D, Sadaghiani AH, Motazakker A, Akkoc Y. Heat exchanger with enhanced heat transfer surfaces. Turkish Patent Institute. Application Number: 17T-10468. April 14, 2017. Pending.
7) Gozuacik D. Usage of FC for cancer diagnosis and treatment. European Patent Office Patent Application Number: EP3067422. March 13, 2013. Pending.
8) Cho YK, Bathany C, Kim JY, Gozuacik D. Device and method for single cell screening-based on inter-cellular communication. WIPO-Patent Cooperation Treaty. Patent Application Number: WO2016099207. June 23, 2016. Pending. USA Patent Office. Patent Number: 10385306. August 20, 2019. Approved.
9) Gozuacik D and Korkmaz G (PhD Student). Use of miRNAs for the diagnosis, propylaxis, treatment and follow-up of diseases involving macroautophagy abnormalities. European Patent Office Patent Number: EP10777121.4. April 05, 2012-2015. Approved.
European Association of Cancer Research (EACR)
American Association of Cancer Research (AACR)
Federation of European Biochemical Societies (FEBS)
International Cell Death Society (ICDS)
Turkish Cell Death Research Association (HÖAD)
Founding Board Member, Turkish Molecular Biology Association (MBD).
2015, Elginkan Foundation Technology Award (with the SUTAB medical device team).
2014, Turkish Press Association, Sedat Simavi Health Sciences Award.
2014, Istanbul Kultur University, Prof. Onder Oztunali Science Award.
2008, Turkish Academy of Sciences Outstanding Young Scientist Award (TUBA-GEBIP Award).
2006, European Molecular Biology Organization, EMBO, Strategical Development and Installation Award.
2006, Selected by Hoffmann-La Roche Pharmaceuticals among the “Leading Bioscientists of the Next Decade”
2004-2006, European Union "Marie Curie Actions" Postdoctoral Fellowship.
2002-2004, Weizmann Institute Feinberg Graduate School Postdoctoral Fellowship.
2001-2002, French Organisation For Medical Research (FRM) Postdoctoral Fellowship.
1999-2001, French Cancer Research Association (ARC) PhD Scholarship.
1996-1999, TUBITAK / NATO A1 PhD Full Scholarship.
