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Mustafa Çulha

Ph.D. in Chemistry

Work Experience

2020-present Researcher Sabanci University Nanotechnology Research & Application Center (SUNUM)
2021-present Visiting Professor, Department of Internal Medicine, Morsani College of Medicine, The University of South Florida, Tampa, FL
2019-2020 Visiting Professor, Oregon Health & Science University, Knight Cancer Research Institute, Cancer Early Detection Advanced Research Center (CEDAR), Portland, Oregon, USA
2004-2019 Professor, Yeditepe University, Department of Genetics and Bioengineering, Istanbul, Turkey
2003-2004 Investigator, Schering-Plough Corporation, Global Quality Services-Analytical Sciences, Implementation of New Technology Department, Union, NJ, USA
2002-2003 Post-Doctoral Research Associate, Advanced Biomedical Science & Technology Group, Oak Ridge National Laboratory, Oak Ridge, TN, USA

Research Interests

  • Applications of surface-enhanced Raman scattering in medicine: cancer diagnosis, detection and identification of pathogens, biofilms and proteins.
  • Synthesis, self-assembly and applications of novel nanomaterials and nanocarriers for delivery of cancer therapeutics.
  • Nanomedicine and nanomaterial surface chemistry nanotoxicity relationship

Last 5 Publications

  1. Deniz Yılmaz and Mustafa Culha, Investigation of the Pathway Dependent Endocytosis of Gold Nanoparticles by Surface-Enhanced Raman Scattering, Talanta (2021). Volume 225, 122071
  2. Hulya Yilmaz, Zehra Cobandede, Deniz Yilmaz, Ayse Cinkilic, Mustafa Culha, Ebru Cubuk Demiralay. Monitoring forced degradation of drugs using silica coated AgNPs with surface-enhanced Raman scattering, Talanta (2020), Volume 214, 120828
  3. Seda Keleştemur, Zehra Çobandede, Mustafa Çulha, Biofilm formation of clinically important microorganisms on 2D and 3D poly (methyl methacrylate) substrates: A surface-enhanced Raman scattering study, Colloids and Surfaces B: Biointerfaces, (2020) 188, 110765,
  4. Hexagonal Boron Nitride Nanoparticles for Prostate Cancer Treatment. Melis Emanet Ciofani, Özlem Şen and Mustafa Çulha. ACS Appl. Nano Mater. (2020), 3, 3, 2364–2372.
  5. Irem Culha Taskin, Ozlem Sen, Melis Emanet, Mustafa Culha and Bayram Yilmaz. Hexagonal boron nitrides reduce the oxidative stress on cells. Nanotechnology, (2020) Volume 31, Number 21.


  • Tissue Differentiation Method Based on Surface-enhanced Raman scattering-US Patent No: US 2011/0124014 A1, 2011
  • Synthesis of Oligonucleotide Madiated Au-Ag Core-Shell Nanoparticles-US Patent No: US 2012/0014878 A1, 2012
  • Identification Method Based on Surface-enhanced Raman scattering- US Patent No: US 8,835,128 B2, 2014
  • Production Method for the Boron Nitride Nanotubes-US Patent No: US 9.487,402 B2, 2016
  • A Microorganism Identification Method Based on Surface-enhanced Raman scattering, 2007-G 85368.(US Patent, Granted)
  • A Nanoparticle Aggregation Method, 2007-G-225560 (PCT, Granted)


  • Society for Applied Spectroscopy


  • The best 2nd in Academic Achievement in Engineering Faculty in 2015, 2016, 2017 and 2018.
  • The best 3rd in Academic Raking at Yeditepe University in 2014.
  • Turkish Ministry of Education Fellowship towards MSc and PhD studies 1995-2002